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ZUCKERBERG JEFFCHIU—THEASSOCIATEDPRESS Facebook CEO Mark Zuckerberg, le , and his wife, Priscilla Chan, rehearse for a speech in San Francisco. By Barbara Ortutay TheAssociatedPress SAN FRANCISCO Facebook CEO Mark Zuckerberg has a goal that's even more am- bitious than connecting the entire world to the inter- net: He and his wife want to help eradicate all disease by the end of this century. Zuckerberg and Priscilla Chan are committing $3 bil- lion over the next 10 years to accelerate basic scien- tific research, including the creation of research tools — from software to hardware to yet-undiscovered tech- niques — they hope will ul- timately lead to scientific breakthroughs, the way the microscope and DNA se- quencing have in genera- tions past. The goal, which they are unlikely to live to see ac- complished, is to "cure, pre- vent or manage all disease" in the next 80 or so years. They acknowledge that this might sound a crazy, but point to how far medi- cine and science have come in the last century — with vaccines, statins for heart disease, chemotherapy, and so on — following millennia with little progress. "So if you even just as- sume that we'll be able to continue to make prog- ress on that same trajec- tory, then that implies that by the end of this century we will have been able to solve most of these types of things," Zuckerberg said in an interview. He and Chan have spent the past two years speaking to scientists and other ex- perts to plan the endeavor. He emphasized "that this isn't something where we just read a book and de- cided we're going to do." Through their philan- thropic organization, the Chan Zuckerberg Initia- tive, the commitment in- cludes $600 million to fund a new research center in San Francisco where scien- tific and medical research- ers will work alongside en- gineers on long-term proj- ects spanning years or even decades. The goal is not to focus narrowly on specific ail- ments, such as bone can- cer or Parkinson's disease, but rather to do basic re- search. One example: a cell atlas that maps out all the different types of cells in the body, which could help researchers create various types of drugs. Chan's work as a pediatri- cian seems to be a big driver in their couple's decision to take up this latest cause. "I've been with families where we've hit the limit of what's possible through medicine and science," Chan said. "I've had to tell families devastating diag- noses of leukemia, or that we just weren't able to re- suscitate their child." The couple spoke with The Associated Press in their home in Palo Alto, Cal- ifornia, where their infant daughter, Max, had just wo- ken from a nap. Their dog, Beast, came by to sit briefly during the 25-minute inter- view. Zuckerberg and Chan hope that their effort will inspire other far-reaching efforts and collaboration in science, medicine and engineering, so that basic research is no longer rele- gated to the margins. "We spend 50 times more on health care treating peo- ple who are sick than we spend on science research (to cure) diseases so that people don't get sick in the first place," Zuckerberg said. FacebookCEO,Chan pl ed ge $ 3B t o en d di se as e By Christopher Weber The Associated Press LOS ANGELES A fire- fighter among those bat- tling a central California wildfire died Wednesday and another firefighter was hurt when the water tanker truck they were in overturned near Vanden- berg Air Force base, offi- cials said. The accident hap- pened as firefighting crews gained ground in their effort to contain the 19-square mile fire at the base near launch pads used to send satellites into space. The truck crashed be- fore dawn at a round- about on a two-lane high- way just outside Vanden- berg, said Ventura County Fire Department spokes- man Steve Swindle. There were no other occupants. Ventura County was among several depart- ments that sent more than 1,000 firefighters to the fire, which was 45 percent contained. Firefighters focused Wednesday on the blaze's southeast boundary. Vol- untary evacuation orders were in place for about 400 residents of the San Miguelito Canyon area just off the base near the small city of Lompoc. There were no indica- tions that the fire on unde- veloped and rugged moun- tainous land threatened any structures. Officials said the fire did not pose an immediate threat to the space launch complex. Its cause was un- der investigation. Swindle identified the dead firefighter as Ryan Osler and said the injured firefighter, Adam Price, was hospitalized. The Cali- fornia Highway Patrol was investigating the cause of the crash. Osler was in his 30s and a second-generation fire- fighter, Swindle said. His father also worked for the Ventura County depart- ment. A 1977 wind-whipped fire at Vandenberg killed the base commander, the base fire chief, an assistant chief and a bulldozer op- erator. ACCIDENT Firefighter dies, 1 hurt as 1,000 battle California wildfire By Martin Crutsinger The Associated Press WASHINGTON The Fed- eral Reserve is keeping its key interest rate un- changed but signaling that it will likely raise rates before year's end. The Fed said in a state- ment ending its latest policy meeting Wednes- day that the U.S. job mar- ket has continued to strengthen and economic activity has picked up. But it noted that business in- vestment remains soft and inflation too low and that it wants to see further im- provement in the job mar- ket. The central bank char- acterized the near-term risks to its economic out- look as "roughly bal- anced." It was the first time it has used that wording since late last year, when it most re- cently raised rates. Most analysts have said they think the Fed will next raise rates in December. The Fed said its policy committee had concluded that "the case for an in- crease in the federal funds rate has strengthened but decided, for the time be- ing, to wait for further ev- idence of continued prog- ress toward its objectives." "The Fed appears to be firmly on track for a De- cember hike," Paul Ash- worth, chief US economist at Capital Economics, said after the statement was is- sued. Stock prices rose in the hour after the Fed issued its statement and during a news conference by Chair Janet Yellen that laid out her case for holding off on a rate hike for now. In her news conference, Yellen offered a simple ex- planation for why the Fed didn't raise rates: The economy can still grow without hurting itself. The Fed chair noted that historically low rates haven't caused the econ- omy to overheat as some analysts feared they would. Steady job gains have pulled discouraged workers back into the job market and yet inflation remains below the Fed's 2 percent target rate. ECONOMY Fed keeps key rate unchanged but hints of coming increase 25thAnnual MANTON APPLE FESTIVAL WWW.MANTONAPPLE.COM SATURDAY OCTOBER 1 ST , 2016 9am-4pm •Food •Crafts •Entertainment Apples Apples Apples www.gummsoptical.com (530) 527-2510 1-800-481-LENS (5367) 910MainSt.,SuiteC,RedBluff availableinprescription sunglasses Regular Haircut $ 2 00 off KWIK KUTS FamilyHairSalon 1064SouthMainSt.,RedBluff•529-3540 ANY RETAIL PRODUCT 20 % off withanychemicalserviceof $50 or more Notgoodwithotheroffers Expires 10/31/16 With coupon Reg. $13.95 Smog Check (MOST CARS & PICK-UPS) 527-9841 • 195 S. 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