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ByKarlRitterand Malcolm Ritter The Associated Press STOCKHOLM Tomas Lin- dahl was eating his break- fast in England on Wednes- day when the call came — ostensibly, from the Royal Swedish Academy of Sci- ences. It occurred to him that this might be a hoax, but then the caller started speaking Swedish. It was no joke: Lindahl and two others had won the Nobel Prize in chemis- try for pioneering studies into the way our bodies re- pair damage to DNA. "Their work has pro- vided fundamental knowl- edge of how a living cell functions" and is used in developing new cancer treatments, the academy said. Lindahl, who is Swedish, was honored along with American Paul Modrich and U.S.-Turkish scientist Aziz Sancar for research done in the 1970s and '80s. The men "really laid the foundations for the whole field" of DNA repair, said Alan Ashworth, president of the cancer center at the UniversityofCalifornia,San Francisco. "These really are the fathers of the field." Lindahl, 77, is an emer- itus group leader at the Francis Crick Institute and Emeritus director of Can- cer Research UK at Clare Hall Laboratory in Britain. Modrich, 69, is an inves- tigator at Howard Hughes Medical Institute and pro- fessor at Duke University School of Medicine in Dur- ham, North Carolina. Sancar, also 69, is a pro- fessor at the University of North Carolina School of Medicine in Chapel Hill, North Carolina. He is the second Turk to win a Nobel Prize, after novelist Orhan Pamuk was awarded the literature prize in 2006. Sancar comes from a family of farmers with eight children; neither par- ent received an education but all the children are uni- versity graduates, Sancar told Haber Turk television. He told The Associated Press that he thought the prize would be very impor- tant for Turkey. "Young Turkish scien- tists need a role model showing that they can ac- complish important contri- butions to science," he said. Lindahl told reporters at his laboratory near London that the prize is "a great honor and a fantastic way of winding up my career." Modrich, on vacation in New Hampshire, said he found out about his prize when a colleague emailed congratulations. "I never quite put our work in this class, actu- ally," Modrich told the AP. "It's nice to know other people put it in that class." The prize is worth 8 mil- lion Swedish kronor (about $960,000). Working separately, the laureates broke new ground by mapping and explaining several of the ways a cell repairs its DNA, the molecule that contains our genes. DNA sustains damage in multiple ways, such as when it is copied as cells divide or in response to chemicals or ultraviolet rays from the sun. DNA was thought to be a stable until the 1970s, when Lindahl showed that it gets damaged so often that it seemed human life would be impossible. He re- alized that there must a re- pair mechanism, opening a new field of research, the academy said. Working at Yale Uni- versity, Sancar mapped the mechanism that cells use to repair UV-damaged DNA. Modrich showed how the cell corrects er- rors when DNA is repli- cated during cell division. Some research into de- veloping new cancer drugs is based on the idea of sab- otaging the DNA repair that keeps cancer cells alive. One drug designed to do that is already used to treat advanced ovar- ian cancer, and many oth- ers are being studied, Ash- worth said. Rodney Rothstein, who studies DNA repair at the Columbia University Med- ical Center in New York, said the Nobel award shows the importance of basic research. The award will be handed out along with the other Nobel Prizes on Dec. 10, the anniversary of prize founder Alfred No- bel's death in 1896. CHEMISTRY TriowinsNobelformapping how cells fix DNA damage MAJDIMOHAMMED—THEASSOCIATEDPRESS Undercover Israeli police officers and Israeli soldiers detain a wounded Palestinian demonstrator, being pulled up, during clashes near Ramallah, West Bank, on Wednesday. By Tia Goldenberg The Associated Press JERUSALEM Palestinian assailants carried out a se- ries of stabbings across Is- rael on Wednesday, jolt- ing an anxious country un- nerved by weeks of unrest as clashes between Israeli forces and Palestinian dem- onstrators raged across the West Bank. The violence forced Prime Minister Benjamin Netanyahu to call off a high- profile visit to Germany and prompted him to tell the na- tion to be on "alert" for fur- ther trouble. And in another sign of the tensions, Jeru- salem's mayor, Nir Barkat, was seen carrying an as- sault rifle while visiting an Arab neighborhood. The unrest began three weeks ago and has spread from the confines of a sen- sitive Jerusalem holy site to spots across Israel and the West Bank. In Wednes- day's violence, stabbings oc- curred outside a crowded mall in central Israel, in a southern Israeli town and in the Old City of Jerusa- lem. Israeli forces shot two of the attackers, killing one, while a third was arrested. No Israelis were seriously hurt. Another Palestinian was wounded when he was shot by police after he at- tempted to run over an of- ficer at a West Bank check- point, police said. Netanyahu has threat- ened a tough response to the violence, and Israel has beefed up security in Jeru- salem and the West Bank. It also briefly barred non- resident Palestinians from entering the Old City, home to sensitive holy sites. That ban was lifted shortly be- fore Wednesday's stabbing. In all, four Israelis have been killed in stabbings and a roadside shooting in re- cent days, while five Pales- tinians, including three at- tackers, have been killed. With the attacks spilling into the Israeli heartland, Netanyahu warned Israelis to be on guard. "Civilians are at the fore- front of the war against ter- rorism and must also be on maximum alert," Netan- yahu said, after a meeting with top police officials. Barkat, the Jerusalem mayor, defended his deci- sion to carry a rifle while visiting an Arab neighbor- hood in east Jerusalem on Monday night. His office said he was a former mili- tary officer and licensed to carry the weapon. "Many terror attacks in Jerusalem have been pre- vented or neutralized due to the quick actions and re- sponse of responsible by- standers," it said, noting that earlier this year, the mayor helped stop a knife- wielding Palestinian at- tacker. Adnan Husseini, the top Palestinian official for Je- rusalem, called Barkat's armed appearance "a dec- laration of war" on Pales- tinian residents of the city. "It's incitement for other Israelis to do the same," he said. In the attack outside the mall, which occurred in the city of Petah Tikva, police said civilians apprehended the suspected Palestinian assailant after he stabbed and slightly wounded a man. Earlier Wednesday, po- lice said a 19-year-old Pal- estinian stabbed a soldier while taking his weapon in the southern town of Kiryat Gat. The suspect then fled into a residential building, where he followed a local woman into her apartment before police forces arrived and shot and killed him. And in Jerusalem's Old City, an 18-year-old Pales- tinian woman stabbed an Israeli man who then shot and wounded her. Israelis told to be alert am id w av e of a tt ac ks WEST BANK CLASHES MARY SCHWALM — THE ASSOCIATED PRESS Paul Modrich takes a phone call as he sits on the couch with his dog, Dover, at his vacation home in Rumney, N.H. N EWS D AILY RED BLUFF TEHAMA COUNTY T H E V O I C E O F T E H A M A C O U N T Y S I N C E 1 8 8 5 CallyourDailyNewsadvertisingrepresentative to place your space reservation today! Includes12-monthonlinepublicationon www.redbluffdailynews.com, with page-turn technology & click-thru to advertiser web sites! (530) 527-2151 AdSizes Prices 1/16page (2.4"x2.3") $70 FullColoradd$26 1/8 page (4.9" x 2.3") $100 Full Color add $40 1/4 page (4.9" x 4.75") $160 Full color add $66 1/2 page (vertical 4.9" x 9.65") $285 Full color add $94 1/2 page (horizontal 10" x 4.75") $285 Full color add $94 Full page (10" x 9.65") $510 Full color add $120 Back Page (10" x 9.65") $750 includes full color Honoryourfemaleemployees! 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